about the product

Transparent, colorless, light yellow or brownish yellow liquid

Original product

This product is a fully original Promomed product

On every original product you will see our brand label

Specifications

Name
ENOPARIN®
Dosage form
SOLUTION FOR INJECTION
Nosological classification
Antithrombotic agents
INN
SODIUM ENOXAPARIN
Dosages
10000 anti-Xa IU/ml
ATC code
B01AB05
Active substance
Sodium Enoxaparin
Pharmacotherapeutic group
General therapy drugs

use

Subcutaneously, except in special cases (see the instructions in the leaflet for details)
Prevention of venous thrombosis and embolism during surgical interventions in patients at moderate and high risk
In patients with a moderate risk of thrombosis and embolism (for example, abdominal surgery), the recommended dose of ENOPARIN® is 20 mg once daily subcutaneously. The first injection should be given 2 hours before surgery.
Patients with a high risk of developing thrombosis and embolism (for example, during orthopedic operations, surgical operations in oncology, patients with additional risk factors unrelated to surgery, such as congenital or acquired thrombophilia, malignant neoplasm, bed rest for more than three months, obesity, venous thrombosis in the anamnesis, varicose veins of the lower extremities, pregnancy) the drug is recommended at a dose of 40 mg once a day subcutaneously, with the introduction of the first dose 12 hours before surgery. If earlier preoperative prophylaxis is necessary (for example, in patients at high risk of developing thrombosis and thromboembolism awaiting delayed orthopedic surgery), the last injection should be given 12 hours before surgery and 12 hours after surgery.
The average duration of treatment with ENOPARIN® is 7-10 days. If necessary, therapy can be continued as long as the risk of thrombosis and embolism persists, and until the patient switches to an outpatient regimen.
In case of major orthopedic surgeries, it may be advisable to continue treatment after initial therapy by administering ENOPARIN® at a dose of 40 mg once a day for five weeks.
For patients at high risk of venous thromboembolism who have undergone surgery, abdominal or pelvic surgery due to cancer, it may be advisable to increase the duration of administration of ENOPARIN® at a dose of 40 mg once a day for four weeks.
Prevention of venous thrombosis and embolism in patients on bed rest due to acute therapeutic diseases
The recommended dose of ENOPARIN is 40 mg once a day, subcutaneously, for 6-14 days. Therapy should be continued until the patient is fully switched to outpatient treatment (for a maximum of 14 days).

(For details on other details, see the instructions in the leaflet)

Features of drug administration
The pre-filled disposable syringe is ready for use.
The drug should not be administered intramuscularly!
Subcutaneous injection
Injections should preferably be performed in the patient's "prone" position. When using pre-filled syringes of 20 mg and 40 mg, in order to avoid drug loss, it is not necessary to remove air bubbles from the syringe before injection. Injections should be carried out alternately in the left or right anterolateral or posterolateral surface of the abdomen.
The needle must be inserted vertically (not laterally) into the skin fold, which is assembled and held between the thumb and forefinger until the injection is completed. The skin fold is released only after the injection is completed.
Do not massage the injection site after administration of the drug.

Help

Package leaflet

  • Prevention of venous thrombosis and embolism during surgical interventions in patients at moderate and high risk, especially orthopedic and general surgical
  • interventions, including oncological
  • Prevention of venous thrombosis and embolism in patients on bed rest due to acute therapeutic diseases, including acute heart failure and decompensation of chronic heart failure (NYHA class III or IV), respiratory failure, as well as severe infections and rheumatic diseases with an increased risk of venous thrombosis (see section "Special instructions")
  • Treatment of deep vein thrombosis with or without pulmonary embolism, except in cases of pulmonary embolism requiring thrombolytic therapy or surgery
  • Prevention of thrombosis in the extracorporeal circulation system during hemodialysis
  • Acute coronary syndrome: - treatment of unstable angina and non-ST segment elevation myocardial infarction in combination with oral administration of acetylsalicylic acid; - treatment of acute ST-segment elevation myocardial infarction in patients undergoing drug treatment or subsequent percutaneous coronary intervention (PCI)

Accidental overdose of ENOPARIN® with intravenous, extracorporeal or subcutaneous administration can lead to hemorrhagic complications. When ingested, even in large doses, absorption of the drug is unlikely.

For more information about all possible adverse reactions and the frequency of their occurrence, see the instructions in the leaflet.

  • Hypersensitivity to sodium enoxaparin, heparin or its derivatives, including other low molecular weight heparins
  • Active clinically significant bleeding, as well as conditions and diseases in which there is a high risk of bleeding, including a recent hemorrhagic stroke, acute ulceration of the gastrointestinal tract (GIT), the presence of a malignant neoplasm with a high risk of bleeding, recent operations on the brain and spinal cord, ophthalmic surgery, known or suspected presence of varicose veins esophageal vein dilation, arteriovenous malformations, vascular aneurysms, vascular abnormalities of the spinal cord and brain
  • Spinal or epidural anesthesia or loco-regional anesthesia, when sodium enoxaparin was used for treatment in the previous 24 hours
  • Immuno—mediated - heparin-induced — thrombocytopenia (in the anamnesis) for the last 100 days or the presence of circulating antiplatelet antibodies in the blood
  • Children under 18 years of age, as efficacy and safety in this category of patients have not been established (see section "Special instructions")

The drug ENOPARIN® should not be mixed with other drugs!
No recommended combinations
Drugs that affect hemostasis (systemic salicylates, acetylsalicylic acid in doses that have an anti-inflammatory effect, nonsteroidal anti-inflammatory drugs (NSAIDs), including ketorolac, other thrombolytics (alteplase, reteplase, streptokinase, tenecteplase, urokinase)), it is recommended to cancel before starting therapy with sodium enoxaparin. If necessary, simultaneous use with enoxaparin sodium should be used with caution and careful clinical observation and monitoring of appropriate laboratory parameters should be carried out.

Registration certificate holder
JSC Biochemist, Russian Federation
15A Vasenko St., Saransk, Republic of Mordovia, 430030
Manufacturer
JSC Biochemist, Russian Federation
Address: 15A Vasenko str., Saransk, 430030, Republic of Mordovia
Phone number: +7 (8342) 38 03 68
Email: biohimic@promomed.pro
Internet address: promomed.ru
An organization that accepts consumer claims
JSC Biochemist, Russian Federation
Address: 15A Vasenko str., Saransk, 430030, Republic of Mordovia
Phone number: 8 800 222 95 63; 8 800 777 86 04 ( around the clock)
Email: hot_line@promomed.pro

At a temperature not exceeding 25 ° C. Do not freeze. Keep out of reach of children.

3 years. Do not apply after the expiration date indicated on the package.

Available by prescription